Scaling Statistical Expertise Through Sustainable Tools and Training

RPACT as a long-term partner for methodology, software, and capability building

Friedrich Pahlke, Daniel Sabanés Bové, Gernot Wassmer

RPACT

February 12, 2026

Setting the focus for today📆

  • Building on an established collaboration with Novartis
  • Supporting scalable and sustainable statistical expertise
  • Combining methodology, software, and training
  • Exploring concrete training opportunities for 2026–2028

We are looking forward to continuing our
productive collaboration together!

RPACT - Who we are

RPACT - Trusted by leading pharmaceutical companies 📝

  • Long-term collaborations with global pharmaceutical organizations, e.g, Novartis, Pfizer, Roche, Bayer, J&J, Moderna, Gilead, UCB, Merck, …
  • Productive use of our tools in research and regulated environments
  • Trusted partner for statistical methodology, software, validation, and training

Gernot’s book on Group Sequential & Adaptive Designs

Daniel’s book on Statistical Inference

A proven partnership with Novartis 🤝

  • Long-term collaboration for five years already
  • Continuous SLA-based partnership for rpact (SLA = Service Level Agreement)
  • Productive licensed use of RPACT Cloud
  • Novartis-driven feature development supporting daily workflows
  • Collaboration on various released packages,
    e.g., rpact, rbmi, RobinCar2
  • Collaboration on various new tools,
    e.g., QTD, graphicalMCP GUI and rpact integration, …

Open source with a long-term commitment ✔️

  • Open source as a strategic choice, not an experiment
  • Clear focus on sustainability, validation, and maintainability
  • Reduction of complexity in daily statistical workflows
  • Professional governance with SLA-backed responsibility
  • Continuous evolution driven by real-world user needs
  • Synergy with LLM-based coding tools due to open training material

See also our new 2026 paper here

RPACT products: proven ecosystem 💻

SLA based, custom feature development and license based collaborations:

SLA for rpact for fixed and adaptive clinical trials

New: SLA for crmPack supporting dose escalation trials

Custom feature development for mmrm

Licensed use of RPACT Cloud as professional graphical user interface

Central dashboard RPACT Connect as one-stop-shop for users

Training formats – concrete and scalable 🎓

  • Web-based trainings for broad and efficient knowledge transfer
  • On-site workshops for interactive and advanced topics
  • Role-specific modules (introductory to advanced)
  • Transition from proprietary software to R (structured onboarding for statisticians and established workflows)
  • Tool-focused and methodology-focused training tracks
  • Designed for short-term needs (2026) and long-term capability building (2028)
  • Backed by a curated set of practical vignettes and use cases
  • Experience from 100+ presentations and training courses, including regulatory audiences (FDA)

Executive summary 📝

  • Trusted long-term partner for leading pharmaceutical organizations, incl. Novartis
    • Five years of productive collaboration with SLA for rpact
    • One year of licensed use of RPACT Cloud
  • Sustainable open-source ecosystem combining methodology, software, and validation
  • High user adoption through usability-focused tools and graphical interfaces
  • Lean expert organization with clear ownership and long-term commitment
  • Proven training expertise with online and on-site formats, tailored to customer needs
  • Scalable training formats supporting short-term and long-term capability building